Sedating antihistamines and
Some drugs are fairly strong sedatives and may be used for this action in the short-term treatment of insomnia.Many of the first generation H1 antagonists tend to inhibit response to acetylcholine that is mediated by muscarinic receptors.They are indicated for various types of allergic reactions, and as an adjunctive therapy for anaphylactic reactions.They are also used to relieve preoperative anxiety and tension, facilitate sleep, and reduce postoperative nausea and vomiting.They concluded that pre-exposure treatment with antihistamines in patients with allergic rhinitis may help decrease the risk of developing Eustachian tube dysfunction.There are no studies to date on a possible role of intranasal antihistamines on treatment of middle ear effusion.
It should also be available in a form convenient for patients to carry with them, since it needs to be immediately available whenever and wherever they are eating.
If a serotonin antagonist such as ondansetron is indicated during lactation, the child should be observed for unexpected symptoms. The rapid control of the newly discovered human immunodeficiency virus was greatly facilitated by its small genome (only nine genes) and the discovery of a relatively few host proteins important to the virus life cycle.
It took several decades for a substantial body of opinion to realise that undue emphasis on this one approach could be responsible for poor productivity.
Common side effects include sedation, carbohydrate craving, and weight gain.
Weight gain with TCAs can be substantial, averaging 1 to 3 pounds per month of treatment.